Abstract Compacts of Cu-50 wt. % Zn powders were reduced in cross section to produce multifilamentary thin wires. Swaging and drawing techniques were used to achieve an areal reduction of about 200 without any intermediate anneals. The temperature-dependent electrical resistivity was studied between 300K and 650K. The isothermal irreversible electrical resistivity changes due to anneal effect was studied at 150 C, 250 C, 350 C and 570 C. According to our experimental data, the alloying effect in multifilamentary Cu-Zn system is completed after annealing at temperatures between 150 C and 350 C for 2 days; and the multifilamentary Cu-Zn thin wire can be annealed at least with a few hours at temperatures below 390K without any alloying effect.